Entries by Neale Sterio

Genetically tailored splice-modulating therapy for A-T

Research Project information Principal researcher: Dr Timothy Yu Institute: Harvard and Boston Children’s Hospital Cost: $518,000 over 12 months in partnership with A-TCP Start Date: April 2018 Action for A-T have provided $23,000 towards the initial “Design and Test” stage of a new ASO study developed by the US based A-T Children’s Project. What are the researchers proposing to […]

Cycling for Research

September was a busy month at Action for A-T, with two big groups of supporters Cycling for Research in separate challenges. Our first event took place on 15-16 September, with a team of 35 cyclists covering 250km over two days from Lyon to Bourg d’Oisans. This involved climbing almost 15,000 feet, including taking on the […]

Longitudinal brain changes in childhood A-T

Research Project information Principal researcher: Dr Rob Dineen Institute: University of Nottingham Cost: £92,966 over 18 months in partnership with BrAshA-T Start Date: April 2018 What are the researchers proposing to do? Ataxia Telangiectasia (A-T) is a genetic condition that leads to nervous system problems, particularly loss of coordination of movement that progresses through childhood. In the previous study, […]

Identifying new therapies for blood cancers in patients with A-T

Research Project information Principal researcher: Professor Malcolm Taylor Institute:  University of Birmingham Cost: £128,810.50 over 24 months in partnership with BrAshA-T Start Date: February 2018 What are the researchers proposing to do? Patients with Ataxia Telangiectasia (A-T) have an increased risk of developing blood cancers. These patients do not have a protein called ATM which is important for […]

Unravelling the antibody deficiency in Ataxia Telangiectasia

Research Project information Principal researcher: Associate Professor Mirjam Van der Burg Institute: Leiden University Medical Centre (LUMC), The Netherlands Cost: £100,000 over 24 months Start Date: January 2018 What are the researchers proposing to do? Ataxia Telangiectasia (A-T) is a rare inherited condition characterised by progressive cerebellar ataxia, chromosomal instability, immunodeficiency, and cancer susceptibility. Patients’ lives are shortened, usually […]