Entries by Neale Sterio

Identifying new therapies for blood cancers in patients with A-T

Research Project information Principal researcher:  Professor Malcolm Taylor Institute:  University of Birmingham Cost: £128,810.50 over 24 months in partnership with BrAshA-T Project Completion Date: 31st of January 2020 Project Overview Patients with Ataxia Telangiectasia (A-T) have an increased risk of developing blood cancers. These patients do not have a protein called ATM which is important for response […]

Deciphering the molecular mechanism linking Ataxia-Telangiectasia and Ataxia-Telangiectasia-Like Disorder

Research Project information Principal researcher: Dr John Reynolds Institute: University of Birmingham Cost: £105183.46 over 36 months Start Date: 5th of October 2020 What are the researchers proposing to do? Individuals with Ataxia-Telangiectasia (A-T) and the related disorder Ataxia-Telangiectasia-Like Disorder (ATLD), which are caused by mutations in the ATM gene and MRE11 gene respectively, suffer from progressive degeneration of […]

Genetically tailored splice-modulating therapy for A-T

Research Project information Principal researcher: Dr Timothy Yu Institute: Harvard and Boston Children’s Hospital Cost: $518,000 over 12 months in partnership with A-TCP Start Date: April 2018 Action for A-T have provided $23,000 towards the initial “Design and Test” stage of a new ASO study developed by the US based A-T Children’s Project. What are the researchers proposing to […]

Cycling for Research

September was a busy month at Action for A-T, with two big groups of supporters Cycling for Research in separate challenges. Our first event took place on 15-16 September, with a team of 35 cyclists covering 250km over two days from Lyon to Bourg d’Oisans. This involved climbing almost 15,000 feet, including taking on the […]

Longitudinal brain changes in childhood A-T

Research Project information Principal researcher:  Dr Rob Dineen Institute:  University of Nottingham Cost: £92,966 in partnership with BrAshA-T Duration: 31.5 months (originally 18 months + 7.5 months no-cost extension due to maternity and an additional 6 months no-cost extension due to the COVID pandemic) Project Completion Date: 30th of November 2020 Project Overview In a previous project, […]

Unravelling the antibody deficiency in Ataxia Telangiectasia

Research Project information Principal researcher:  Associate Professor Mirjam Van der Burg Institute:   Leiden University Medical Centre (LUMC), The Netherlands Cost: £100,000 (the team required a no cost extension, taking the project closer to three years rather than the original two years planned) Project Completion Date: 30th of November 2020 Project Overview A-T is characterised by progressive […]

Optimising lung imaging in people with Ataxia Telangiectasia (A-T) applying improved MRI techniques

Research Project information Principal researcher: Dr Peter Merkus Institute: Radboud University Medical Centre, the Netherlands Cost: £87,810 over 36 months Start Date: 1st November 2017 (no cost extension granted until May 2021) What are the researchers proposing to do? The Dutch team will study how they can develop improved lung imaging in A-T patients using advanced MRI techniques […]

WLCF small grant awarded to Action for A-T

Wasps Legends Charitable Foundation, the past players network of Wasps, men and women, amateur and professional announced recently that they have issued a small grant award of £2,500 to Action for A-T. The donation will support work being undertaken at Nottingham University Hospital, which aims to measure the lung heath in A-T patients. This involves a […]