Entries by Neale Sterio

Genetically tailored splice-modulating therapy for A-T

5th November 2023 in , , /by

Research Project information Principal researcher: Dr Timothy Yu Institute: Harvard and Boston Children’s Hospital Cost: $518,000 over 12 months in partnership with A-TCP Completion date: Still ongoing Action for A-T provided $23,000 towards the initial “Design and Test” stage of a new ASO study developed by the US based A-T Children’s Project. Project Overview Several ASO drugs have […]

Identifying new therapies for blood cancers in patients with A-T

14th September 2020 in , , /by

Research Project information Principal researcher:  Professor Malcolm Taylor Institute:  University of Birmingham Cost: £95,373 over 24 months in partnership with BrAshA-T Project Completion Date: 31st of January 2020 Project Overview Patients with Ataxia Telangiectasia (A-T) have an increased risk of developing blood cancers. These patients do not have a protein called ATM which is important for […]

Cycling for Research

3rd October 2018 in /by

September was a busy month at Action for A-T, with two big groups of supporters Cycling for Research in separate challenges. Our first event took place on 15-16 September, with a team of 35 cyclists covering 250km over two days from Lyon to Bourg d’Oisans. This involved climbing almost 15,000 feet, including taking on the […]

Longitudinal brain changes in childhood A-T

18th April 2018 in , , /by

Research Project information Principal researcher:  Dr Rob Dineen Institute:  University of Nottingham Cost: £85,841 in partnership with BrAshA-T Duration: 31.5 months (originally 18 months + 7.5 months no-cost extension due to maternity and an additional 6 months no-cost extension due to the COVID pandemic) Project Completion Date: 30th of November 2020 Project Overview In a previous […]

Unravelling the antibody deficiency in Ataxia Telangiectasia

17th January 2018 in , , /by

Research Project information Principal researcher:  Associate Professor Mirjam Van der Burg Institute:   Leiden University Medical Centre (LUMC), The Netherlands Cost: £100,000 (the team required a no cost extension, taking the project closer to three years rather than the original two years planned) Project Completion Date: 30th of November 2020 Project Overview A-T is characterised by progressive […]

WLCF small grant awarded to Action for A-T

13th June 2017 in /by

Wasps Legends Charitable Foundation, the past players network of Wasps, men and women, amateur and professional announced recently that they have issued a small grant award of £2,500 to Action for A-T. The donation will support work being undertaken at Nottingham University Hospital, which aims to measure the lung heath in A-T patients. This involves a […]

A zebrafish model of Ataxia Telangiectasia (A-T)

7th February 2017 in , , /by

Research Project information Principal researcher:  Dr Andrew Grierson Institute: Sheffield Institute for Translational Neuroscience (SITraN) & The Bateson Centre, University of Sheffield Cost: £88,710 over 36 months Project Completion Date: June 2020 Project Overview Almost all human disease genes (approx. 70%) have an equivalent in zebrafish. While humans and zebrafish may not look alike, they are similar. Zebrafish […]