Entries by Neale Sterio

Identifying new therapies for blood cancers in patients with A-T

Research Project information Principal researcher:  Professor Malcolm Taylor Institute:  University of Birmingham Cost: £128,810.50 over 24 months in partnership with BrAshA-T Project Completion Date: 31st of January 2020 Project Overview Patients with Ataxia Telangiectasia (A-T) have an increased risk of developing blood cancers. These patients do not have a protein called ATM which is important for response […]

Deciphering the molecular mechanism linking Ataxia-Telangiectasia and Ataxia-Telangiectasia-Like Disorder

Research Project information Principal researcher: Dr John Reynolds Institute: University of Birmingham Cost: £105183.46 over 36 months Start Date: 5th of October 2020 What are the researchers proposing to do? Individuals with Ataxia-Telangiectasia (A-T) and the related disorder Ataxia-Telangiectasia-Like Disorder (ATLD), which are caused by mutations in the ATM gene and MRE11 gene respectively, suffer from progressive degeneration of […]

Genetically tailored splice-modulating therapy for A-T

Research Project information Principal researcher: Dr Timothy Yu Institute: Harvard and Boston Children’s Hospital Cost: $518,000 over 12 months in partnership with A-TCP Start Date: April 2018 Action for A-T have provided $23,000 towards the initial “Design and Test” stage of a new ASO study developed by the US based A-T Children’s Project. What are the researchers proposing to […]

Cycling for Research

September was a busy month at Action for A-T, with two big groups of supporters Cycling for Research in separate challenges. Our first event took place on 15-16 September, with a team of 35 cyclists covering 250km over two days from Lyon to Bourg d’Oisans. This involved climbing almost 15,000 feet, including taking on the […]

Longitudinal brain changes in childhood A-T

Research Project information Principal researcher: Dr Rob Dineen Institute: University of Nottingham Cost: £92,966 over 18 months in partnership with BrAshA-T Start Date: April 2018 (6 month extension to May 2020 granted in March 2019) What are the researchers proposing to do? Ataxia Telangiectasia (A-T) is a genetic condition that leads to nervous system problems, particularly loss of coordination of […]