Entries by Sean Kelly

Royal Parks Half Marathon

8th October 2017 The Royal Parks Foundation Half Marathon takes place each October, starting and finishing in the stunning Hyde Park. Over 16,000 runners take part in the 13.1 mile route through Central London, taking in the spectacular sites of the capital and the beautiful Royal Parks. As well as all of the fantastic runners that […]

Therapeutic strategies for offsetting Neurological Sequelae in A-T

Research Project Information Principal researchers: Dr. Margot Mayer-Proschel Institute: University of Rochester, United States of America Grant award: Funded in partnership with the A-T Children’s Project Project completion date: July 2015 Project Overview Ataxi Telangiectasia (A-T) is caused by faults in a gene called ATM (Ataxia Telangiectasia Mutated), which results in the ATM protein not functioning correctly. […]

Neurons from blood-derived stem cells as a model of A-T neurodegeneration.

Research Project Information Principal Researchers: Professor Ron Hart Institute: University of Rutgers, United States of America Project Completion Date: April 2015  Project Overview Ataxia Telangiectasia (A-T) is caused by defects in the ATM (Ataxia Telangiectasia Mutated) gene and the associated ATM protein. Similar to other neurodegenerative conditions, such as Alzheimer’s and Parkinson’s disease, some of […]

Investigating the potential of targeting resident neural stem cells in Ataxia Telangiectasia.

Research Project Information Principal researchers: Professor Paul Wong Institute: MD Anderson Cancer Centre, University of Texas, USA Project completion date: December 2013 Project Overview Ataxia-telangiectasia (A-T) is caused by faults in a gene called ATM (Ataxia-Telangiectasia Mutated). Similar to Alzheimer’s and Parkinson’s disease, some of the most destructive symptoms are due to the death of nerve cells (neurons) […]

PCD Mice as an animal model of Ataxia in A-T.

Research Project Information Principal researchers: Professor Kamran Khodakhah Institute: Albert Einstein College of Medicine, USA Grant award: Funded in partnership with the A-T Children’s Project Project completion date: July 2013 Project Overview One of the symptoms of ataxia telangiectasia (A-T) is a progressive loss of muscle coordination called ataxia. Unfortunately, no current treatments can prevent this process. For effective […]

Linking Neurodegeneration to Protein Turnover in Ataxia Telangiectasia

Research Project Information Principal researchers: Professor Shyamal Desai Institute: Louisiana State University Health Sciences Centre, United States of America Grant awarded: Funded in partnership with the A-T Children’s Project Project completion date: July 2013 Project Overview Nerve cells (neurons) within the brain of Ataxia Telangiectasia (A-T) patients are defective in repairing damaged DNA. Consequently, A-T […]

Investigating Connectivity and Neuroinflammation within Corticomotor Networks in Ataxia Telangiectasia: Improving our Understanding of the Clinical Phenotype

Research Project Information Principal Researchers: Professor Stephen Rose Institute: Royal Children’s Hospital, University of Queensland, Australia Project Completion Date: July 2013  Project Overview  Ataxia Telangiectasia (A-T) is caused by faults in a gene called ATM (Ataxia Telangiectasia Mutated). A range of symptoms are observed, including the loss of muscle coordination (ataxia) due to the damage […]